Dovitinib [CAS 405169-16-6]

Size 5 mg 10 mM - 1 mL 10 mg 25 mg 50 mg 100 mg

SKU:QM-0156517-01

£78.82 GBP

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Product Details

Description
Dovitinib (CHIR-258) is an orally active, potent multi-targeted tyrosine kinase (RTK) inhibitor with IC50s of 1, 2, 36, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, CSF-1R, FGFR1/FGFR3, VEGFR1/VEGFR2/VEGFR3 and PDGFRα/PDGFRβ, respectively. Dovitinib has potent antitumor activity[1][2].
CAS Number
[405169-16-6]
Molecular Formula
C21H21FN6O
Molecular Weight
392.43
Smiles
O=C1NC(C=CC=C2F)=C2C(N)=C1C3=NC4=CC=C(N5CCN(C)CC5)C=C4N3
Target
C-Fms; c-Kit; FGFR; FLT3; PDGFR; VEGFR
Isoform
PDGFRα; PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4
Purity
99.88
Solubility
DMSO : 23.33 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0156517-01	5 mgQM-0156517-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

10 mM - 1 mLQM-0156517-02	10 mM - 1 mLQM-0156517-02 £89.13/ea	£0.00	Quantity	£89.13/ea	£0.00

10 mgQM-0156517-03	10 mgQM-0156517-03 £118.38/ea	£0.00	Quantity	£118.38/ea	£0.00

25 mgQM-0156517-04	25 mgQM-0156517-04 £250.47/ea	£0.00	Quantity	£250.47/ea	£0.00

50 mgQM-0156517-05	50 mgQM-0156517-05 £376.83/ea	£0.00	Quantity	£376.83/ea	£0.00

100 mgQM-0156517-06	100 mgQM-0156517-06 £577.31/ea	£0.00	Quantity	£577.31/ea	£0.00

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Dovitinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.