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Dovitinib (lactate) [CAS 692737-80-7]
Dovitinib (lactate) [CAS 692737-80-7]
SKU:QM-0081804-01
£94.75 GBP
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Product Details
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Description
Dovitinib lactate (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively[1].
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CAS Number
[692737-80-7]
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Molecular Formula
C24H27FN6O4
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Molecular Weight
482.51
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Smiles
O=C(N1)C(C(NC2=C3)=NC2=CC=C3N4CCN(C)CC4)=C(N)C5=C1C=CC=C5F.O=C(O)C(C)O
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Target
C-Kit; FGFR; FLT3; PDGFR; VEGFR
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Isoform
PDGFRα; PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4
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Purity
99.75
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Solubility
DMSO : 25 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Dovitinib (lactate) [CAS 692737-80-7]
Dovitinib (lactate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.