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Erlotinib [CAS 183321-74-6]

Erlotinib [CAS 183321-74-6]

Size

QM-0156501-01

£101.50 GBP
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Product Details

  • Description

    Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • CAS Number

    [183321-74-6]

  • Molecular Formula

    C22H23N3O4

  • Molecular Weight

    393.44

  • Smiles

    C#CC1=CC=CC(NC2=NC=NC3=C2C=C(C(OCCOC)=C3)OCCOC)=C1

  • Target

    Autophagy; EGFR

  • Isoform

    EGFR/ErbB1/HER1

  • Purity

    99.99

  • Solubility

    DMSO : 33.33 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
100 mgQM-0156501-01
100 mgQM-0156501-01
£101.50/ea		 £0.00
£101.50/ea £0.00
500 mgQM-0156501-02
500 mgQM-0156501-02
£131.88/ea		 £0.00
£131.88/ea £0.00
1 gQM-0156501-03
1 gQM-0156501-03
£244.40/ea		 £0.00
£244.40/ea £0.00
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Erlotinib [CAS 183321-74-6]

Erlotinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.