Imatinib [CAS 152459-95-5]
Imatinib [CAS 152459-95-5]
SKU:QM-0151495-01
Couldn't load pickup availability
Request quote or documents
![Imatinib [CAS 152459-95-5]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively[1][2][3][4]. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV[5].
-
CAS Number
[152459-95-5]
-
Molecular Formula
C29H31N7O
-
Molecular Weight
493.6
-
Smiles
CN(CC1)CCN1CC2=CC=C(C(NC3=CC=C(C)C(NC4=NC(C5=CC=CN=C5)=CC=N4)=C3)=O)C=C2
-
Target
Autophagy; Bcr-Abl; c-Kit; PDGFR; SARS-CoV
-
Concentration
10mM
-
Purity
99.95
-
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
-
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H361
-
Precautions
H361
Related Products
- QM-0081895-01 Sunitinib (Standard) [CAS 557795-19-4]
- QM-0081894-01 Sunitinib [CAS 557795-19-4]
- QM-0081897-01 Sunitinib (Malate) (Standard) [CAS 341031-54-7]
- QM-0081893-01 Sunitinib (Malate) [CAS 341031-54-7]
- QM-0081750-01 Sorafenib (Standard) [CAS 284461-73-0]
- QM-0081737-01 Sorafenib [CAS 284461-73-0]
- QM-0081749-01 Sorafenib (tosylate) (Standard) [CAS 475207-59-1]
- QM-0081748-01 Sorafenib (tosylate) [CAS 475207-59-1]
- QM-0004618-01 SP600125 (Standard) [CAS 129-56-6]
- QM-0139909-01 SP600125 [CAS 129-56-6]
Other industry favorites
- QM-0081895-01 Sunitinib (Standard) [CAS 557795-19-4]
- QM-0081894-01 Sunitinib [CAS 557795-19-4]
- QM-0076735-01 Ribociclib (Standard) [CAS 1211441-98-3]
- QM-0152381-01 Ribociclib [CAS 1211441-98-3]
- QM-0002216-01 PI-103 (Standard) [CAS 371935-74-9]
- QM-0077718-01 PI-103 [CAS 371935-74-9]
- QM-0017434-01 Selumetinib (Standard) [CAS 606143-52-6]
- QM-0156439-01 Selumetinib [CAS 606143-52-6]
- QM-0086090-01 Quizartinib (Standard) [CAS 950769-58-1]
- QM-0143019-01 Quizartinib [CAS 950769-58-1]
Imatinib [CAS 152459-95-5]
Imatinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.