Lapatinib (ditosylate) [CAS 388082-77-7]

Size 50 mg 10 mM - 1 mL 100 mg 500 mg 1 g

SKU:QM-0156505-01

£101.50 GBP

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Product Details

Description
Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively[1].
CAS Number
[388082-77-7]
Molecular Formula
C43H42ClFN4O10S3
Molecular Weight
925.46
Smiles
O=S(CCNCC1=CC=C(C2=CC=C3C(C(NC4=CC(Cl)=C(C=C4)OCC5=CC(F)=CC=C5)=NC=N3)=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O
Target
Autophagy; EGFR; Ferroptosis
Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
Purity
99.98
Solubility
DMSO : 125 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
50 mgQM-0156505-01	50 mgQM-0156505-01 £101.50/ea	£0.00	Quantity	£101.50/ea	£0.00

10 mM - 1 mLQM-0156505-02	10 mM - 1 mLQM-0156505-02 £109.38/ea	£0.00	Quantity	£109.38/ea	£0.00

100 mgQM-0156505-03	100 mgQM-0156505-03 £125.13/ea	£0.00	Quantity	£125.13/ea	£0.00

500 mgQM-0156505-04	500 mgQM-0156505-04 £266.27/ea	£0.00	Quantity	£266.27/ea	£0.00

1 gQM-0156505-05	1 gQM-0156505-05 £299.07/ea	£0.00	Quantity	£299.07/ea	£0.00

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Lapatinib (ditosylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.