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Leptomycin B [CAS 87081-35-4]

Leptomycin B [CAS 87081-35-4]

Size

QM-0154231-01

£376.83 GBP
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Product Details

  • Description

    Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1].

  • CAS Number

    [87081-35-4]

  • Molecular Formula

    C33H48O6

  • Molecular Weight

    540.73

  • Smiles

    O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(CC)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O

  • Target

    Antibiotic; CRM1; Fungal

  • Purity

    99.94

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C (Powder, stored under nitrogen)

  • Shipping Conditions

    Blue Ice

  • Hazard Statement

    H302, H312, H332

  • Precautions

    H302, H312, H332
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Variant Variant total Quantity Price Variant total
1 mgQM-0154231-01
1 mgQM-0154231-01
£376.83/ea		 £0.00
£376.83/ea £0.00
5 mgQM-0154231-02
5 mgQM-0154231-02
£1,241.91/ea		 £0.00
£1,241.91/ea £0.00
10 mgQM-0154231-03
10 mgQM-0154231-03
£1,933.25/ea		 £0.00
£1,933.25/ea £0.00
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Leptomycin B [CAS 87081-35-4]

Leptomycin B is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.