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Masitinib [CAS 790299-79-5]

Masitinib [CAS 790299-79-5]

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SKU:QM-0081824-01

£51.91 GBP
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  • Description

    Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit (IC50=200 nM for human recombinant c-Kit) . It also inhibits PDGFRα/β (IC50s=540/800 nM), Lyn (IC50= 510 nM for LynB), Lck, and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity[1][2][4].

  • CAS Number

    [790299-79-5]

  • Molecular Formula

    C28H30N6OS

  • Molecular Weight

    498.64

  • Smiles

    O=C(NC1=CC=C(C(NC2=NC(C3=CC=CN=C3)=CS2)=C1)C)C4=CC=C(CN5CCN(CC5)C)C=C4

  • Target

    Apoptosis; c-Kit; FAK; FGFR; PDGFR; Src

  • Purity

    99.95

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0081824-01
5 mgQM-0081824-01
£51.91/ea
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£51.91/ea £0.00
10 mgQM-0081824-02
10 mgQM-0081824-02
£62.26/ea
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£62.26/ea £0.00
50 mgQM-0081824-03
50 mgQM-0081824-03
£129.63/ea
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£129.63/ea £0.00
100 mgQM-0081824-04
100 mgQM-0081824-04
£232.25/ea
£0.00
£232.25/ea £0.00
200 mgQM-0081824-05
200 mgQM-0081824-05
£325.81/ea
£0.00
£325.81/ea £0.00

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Masitinib [CAS 790299-79-5]

Masitinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.