Nintedanib esylate [CAS 656247-18-6]

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SKU:QM-0136907-01

£63.29 GBP

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Product Details

Description
Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively.
CAS Number
[656247-18-6]
Molecular Formula
C33H39N5O7S
Molecular Weight
649.76
Smiles
O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)OC.CCS(=O)(O)=O
Target
FGFR; PDGFR; VEGFR
Isoform
PDGFRα; PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4
Purity
99.96
Solubility
DMSO : 66.67 mg/mL (ultrasonic) |Ethanol : 3.08 mg/mL (ultrasonic) |H2O : 16.67 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
10 mM - 1 mLQM-0136907-01	10 mM - 1 mLQM-0136907-01 £63.29/ea	£0.00	Quantity	£63.29/ea	£0.00

10 mgQM-0136907-02	10 mgQM-0136907-02 £65.37/ea	£0.00	Quantity	£65.37/ea	£0.00

50 mgQM-0136907-03	50 mgQM-0136907-03 £136.38/ea	£0.00	Quantity	£136.38/ea	£0.00

100 mgQM-0136907-04	100 mgQM-0136907-04 £215.24/ea	£0.00	Quantity	£215.24/ea	£0.00

200 mgQM-0136907-05	200 mgQM-0136907-05 £306.37/ea	£0.00	Quantity	£306.37/ea	£0.00

500 mgQM-0136907-06	500 mgQM-0136907-06 £561.51/ea	£0.00	Quantity	£561.51/ea	£0.00

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Nintedanib esylate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.