Niraparib [CAS 1038915-60-4]

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SKU:QM-0112094-01

£106.00 GBP

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Product Details

Description
Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
CAS Number
[1038915-60-4]
Molecular Formula
C19H20N4O
Molecular Weight
320.39
Smiles
NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O
Target
Apoptosis; PARP
Isoform
PARP1; PARP2; PARP3; PARP4; TNKS1/PARP5A
Purity
99.96
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0112094-01	5 mgQM-0112094-01 £106.00/ea	£0.00	Quantity	£106.00/ea	£0.00

10 mM - 1 mLQM-0112094-02	10 mM - 1 mLQM-0112094-02 £115.00/ea	£0.00	Quantity	£115.00/ea	£0.00

10 mgQM-0112094-03	10 mgQM-0112094-03 £140.88/ea	£0.00	Quantity	£140.88/ea	£0.00

50 mgQM-0112094-04	50 mgQM-0112094-04 £275.99/ea	£0.00	Quantity	£275.99/ea	£0.00

100 mgQM-0112094-05	100 mgQM-0112094-05 £401.13/ea	£0.00	Quantity	£401.13/ea	£0.00

500 mgQM-0112094-06	500 mgQM-0112094-06 £902.93/ea	£0.00	Quantity	£902.93/ea	£0.00

1 gQM-0112094-07	1 gQM-0112094-07 £1,405.94/ea	£0.00	Quantity	£1,405.94/ea	£0.00

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Niraparib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.