Niraparib (tosylate) [CAS 1038915-73-9]

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SKU:QM-0112099-01

£115.00 GBP

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Product Details

Description
Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
CAS Number
[1038915-73-9]
Molecular Formula
C26H28N4O4S
Molecular Weight
492.59
Smiles
NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O
Target
Apoptosis; PARP
Isoform
PARP1; PARP2; PARP3; PARP4; TNKS1/PARP5A
Purity
99.99
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 1 mg/mL (heat to 50°C)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature
Hazard Statement
H302, H315, H319, H335
Precautions
H302, H315, H319, H335

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0112099-01	5 mgQM-0112099-01 £115.00/ea	£0.00	Quantity	£115.00/ea	£0.00

10 mM - 1 mLQM-0112099-02	10 mM - 1 mLQM-0112099-02 £124.00/ea	£0.00	Quantity	£124.00/ea	£0.00

10 mgQM-0112099-03	10 mgQM-0112099-03 £188.51/ea	£0.00	Quantity	£188.51/ea	£0.00

50 mgQM-0112099-04	50 mgQM-0112099-04 £299.07/ea	£0.00	Quantity	£299.07/ea	£0.00

100 mgQM-0112099-05	100 mgQM-0112099-05 £436.37/ea	£0.00	Quantity	£436.37/ea	£0.00

500 mgQM-0112099-06	500 mgQM-0112099-06 £902.93/ea	£0.00	Quantity	£902.93/ea	£0.00

1 gQM-0112099-07	1 gQM-0112099-07 £1,405.94/ea	£0.00	Quantity	£1,405.94/ea	£0.00

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Niraparib (tosylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.