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Osimertinib [CAS 1421373-65-0]

Osimertinib [CAS 1421373-65-0]

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SKU:QM-0152364-01

£94.75 GBP
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  • Description

    Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M, respectively. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].

  • CAS Number

    [1421373-65-0]

  • Molecular Formula

    C28H33N7O2

  • Molecular Weight

    499.61

  • Smiles

    C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O

  • Target

    EGFR

  • Isoform

    EGFR/ErbB1/HER1

  • Purity

    99.99

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0152364-01
5 mgQM-0152364-01
£94.75/ea
£0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0152364-02
10 mM - 1 mLQM-0152364-02
£101.50/ea
£0.00
£101.50/ea £0.00
10 mgQM-0152364-03
10 mgQM-0152364-03
£106.00/ea
£0.00
£106.00/ea £0.00
50 mgQM-0152364-04
50 mgQM-0152364-04
£140.88/ea
£0.00
£140.88/ea £0.00
100 mgQM-0152364-05
100 mgQM-0152364-05
£200.66/ea
£0.00
£200.66/ea £0.00
200 mgQM-0152364-06
200 mgQM-0152364-06
£226.18/ea
£0.00
£226.18/ea £0.00
500 mgQM-0152364-07
500 mgQM-0152364-07
£250.47/ea
£0.00
£250.47/ea £0.00
1 gQM-0152364-08
1 gQM-0152364-08
£288.14/ea
£0.00
£288.14/ea £0.00

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Osimertinib [CAS 1421373-65-0]

Osimertinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.