Osimertinib (mesylate) [CAS 1421373-66-1]

Size 5 mg 10 mg 10 mM - 1 mL 50 mg 100 mg 200 mg 500 mg 1 g

SKU:QM-0152366-01

£94.75 GBP

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Product Details

Description
Osimertinib mesylate (AZD9291 mesylate) is a covalent, orally active, irreversible, and mutant-selective EGFR inhibitor with an apparent IC50 of 12 nM against L858R and 1 nM against L858R/T790M. Osimertinib overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer[1].
CAS Number
[1421373-66-1]
Molecular Formula
C29H37N7O5S
Molecular Weight
595.71
Smiles
C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O
Target
EGFR
Isoform
EGFR/ErbB1/HER1
Purity
99.97
Solubility
DMSO : 11.67 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Shipping Conditions
Room Temperature
Hazard Statement
H315, H319, H335
Precautions
H315, H319, H335

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0152366-01	5 mgQM-0152366-01 £94.75/ea	£0.00	Quantity	£94.75/ea	£0.00

10 mgQM-0152366-02	10 mgQM-0152366-02 £106.00/ea	£0.00	Quantity	£106.00/ea	£0.00

10 mM - 1 mLQM-0152366-03	10 mM - 1 mLQM-0152366-03 £117.25/ea	£0.00	Quantity	£117.25/ea	£0.00

50 mgQM-0152366-04	50 mgQM-0152366-04 £140.88/ea	£0.00	Quantity	£140.88/ea	£0.00

100 mgQM-0152366-05	100 mgQM-0152366-05 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

200 mgQM-0152366-06	200 mgQM-0152366-06 £226.18/ea	£0.00	Quantity	£226.18/ea	£0.00

500 mgQM-0152366-07	500 mgQM-0152366-07 £250.47/ea	£0.00	Quantity	£250.47/ea	£0.00

1 gQM-0152366-08	1 gQM-0152366-08 £288.14/ea	£0.00	Quantity	£288.14/ea	£0.00

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Osimertinib (mesylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.