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Pazopanib [CAS 444731-52-6]
Pazopanib [CAS 444731-52-6]
SKU:QM-0081812-01
£57.09 GBP
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Product Details
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Description
Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
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CAS Number
[444731-52-6]
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Molecular Formula
C21H23N7O2S
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Molecular Weight
437.53
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Smiles
O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O
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Target
Autophagy; c-Kit; FGFR; PDGFR; VEGFR
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Isoform
PDGFRβ; VEGFR1/Flt-1; VEGFR2/KDR/Flk-1; VEGFR3/Flt-4
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Purity
99.91
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Solubility
DMSO : 50 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Pazopanib [CAS 444731-52-6]
Pazopanib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.