PD98059 [CAS 167869-21-8]

Size 5 mg 10 mg 10 mM - 1 mL 50 mg 100 mg

SKU:QM-0139861-01

£67.44 GBP

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Product Details

Description
PD98059 is a potent and selective MEK inhibitor with an IC50 of 5 µM. PD98059 binds to the inactive form of MEK, thereby preventing the activation of MEK1 (IC50 of 2-7 µM) and MEK2 (IC50 of 50 µM) by upstream kinases. PD98059 is a ERK1/2 signaling inhibitor. PD98059 is a ligand for the aryl hydrocarbon receptor (AHR), and suppresses TCDD binding (IC50 of 4 μM) and AHR transformation (IC50 of 1 μM) . PD98059 also inhibits Mycobacterium bovis Bacillus CalmetteGuerin (BCG) -induced autophagy[1][2][3].
CAS Number
[167869-21-8]
Molecular Formula
C16H13NO3
Molecular Weight
267.28
Smiles
O=C1C=C(OC2=CC=CC=C21)C3=CC=CC(OC)=C3N
Target
Aryl Hydrocarbon Receptor; Autophagy; ERK; MEK
Isoform
ERK1; ERK2; MEK1; MEK2
Purity
99.96
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature
Hazard Statement
H301
Precautions
H301

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0139861-01	5 mgQM-0139861-01 £67.44/ea	£0.00	Quantity	£67.44/ea	£0.00

10 mgQM-0139861-02	10 mgQM-0139861-02 £94.75/ea	£0.00	Quantity	£94.75/ea	£0.00

10 mM - 1 mLQM-0139861-03	10 mM - 1 mLQM-0139861-03 £101.50/ea	£0.00	Quantity	£101.50/ea	£0.00

50 mgQM-0139861-04	50 mgQM-0139861-04 £215.24/ea	£0.00	Quantity	£215.24/ea	£0.00

100 mgQM-0139861-05	100 mgQM-0139861-05 £336.74/ea	£0.00	Quantity	£336.74/ea	£0.00

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PD98059 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.