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Ponatinib [CAS 943319-70-8]

Ponatinib [CAS 943319-70-8]

Size

QM-0139926-01

£69.50 GBP
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Product Details

  • Description

    Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively[1].

  • CAS Number

    [943319-70-8]

  • Molecular Formula

    C29H27F3N6O

  • Molecular Weight

    532.56

  • Smiles

    CC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5

  • Target

    Autophagy; Bcr-Abl; FGFR; PDGFR; Src; VEGFR

  • Isoform

    PDGFRα; VEGFR2/KDR/Flk-1

  • Purity

    99.67

  • Solubility

    DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H301, H311, H315, H319, H331, H335

  • Precautions

    H301, H311, H315, H319, H331, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0139926-01
5 mgQM-0139926-01
£69.50/ea		 £0.00
£69.50/ea £0.00
10 mgQM-0139926-02
10 mgQM-0139926-02
£101.50/ea		 £0.00
£101.50/ea £0.00
10 mM - 1 mLQM-0139926-03
10 mM - 1 mLQM-0139926-03
£109.38/ea		 £0.00
£109.38/ea £0.00
50 mgQM-0139926-04
50 mgQM-0139926-04
£139.75/ea		 £0.00
£139.75/ea £0.00
100 mgQM-0139926-05
100 mgQM-0139926-05
£248.04/ea		 £0.00
£248.04/ea £0.00
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Ponatinib [CAS 943319-70-8]

Ponatinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.