Tacrolimus [CAS 104987-11-3]

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SKU:QM-0146039-01

£59.16 GBP

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Product Details

Description
Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1].
CAS Number
[104987-11-3]
Molecular Formula
C44H69NO12
Molecular Weight
804.02
Smiles
O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O
Target
Antibiotic; Autophagy; Bacterial; FKBP; Phosphatase
Isoform
Macrolide
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic) |Ethanol : 12.5 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature
Hazard Statement
H301, H361, H372
Precautions
H301, H361, H372

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0146039-01	5 mgQM-0146039-01 £59.16/ea	£0.00	Quantity	£59.16/ea	£0.00

10 mgQM-0146039-02	10 mgQM-0146039-02 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

50 mgQM-0146039-03	50 mgQM-0146039-03 £122.88/ea	£0.00	Quantity	£122.88/ea	£0.00

100 mgQM-0146039-04	100 mgQM-0146039-04 £207.95/ea	£0.00	Quantity	£207.95/ea	£0.00

200 mgQM-0146039-05	200 mgQM-0146039-05 £275.99/ea	£0.00	Quantity	£275.99/ea	£0.00

500 mgQM-0146039-06	500 mgQM-0146039-06 £441.23/ea	£0.00	Quantity	£441.23/ea	£0.00

1 gQM-0146039-07	1 gQM-0146039-07 £614.98/ea	£0.00	Quantity	£614.98/ea	£0.00

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Tacrolimus is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.